| 摘要: |
| 采用体外慢性毒性实验，研究了3种重金属离子Cd2+、Hg2+和Zn2+对刺参(Apostichopus japonicus)幼参内脏超氧化物歧化酶(SOD)活性的影响。结果表明，随着3种重金属离子暴露时间的延长，幼参SOD活性发生了明显的变化。0.009～0.046 mg/L的Hg2+ 对SOD活性的影响在24 h和48 h时表现为诱导效应，96 h的SOD值达到最大，144 h的SOD值下降。0.195～0.976 mg/L的Zn2+对幼参SOD活性的影响48 h表现为诱导效应，96 h和144 h的SOD活性下降。Hg2+和Zn2+对幼参SOD活性的影响，均表现为随暴露时间延长，先诱导后抑制的趋势。0.214～1.069 mg/L的Cd2+ 对幼参SOD活性的影响48 h表现为抑制效应，96 h和144 h表现为诱导效应。 |
| 关键词: 刺参(Apostichopus japonicus) Cd2+ Hg2+ Zn2+ SOD |
| DOI： |
| 分类号: |
| 基金项目:山东省科技发展计划项目（2008GG10005023）；鲁东大学科研基金重点项目（L20073305） |
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| Effect of heavy metal on the SOD activity of the viscera of Apostichopus japonicus juvenile |
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SUN Zhen-xing,ZHANG Mei-zhen,XU Bing-qing,LIU Yang1,TANG Yu-xia,SONG Zhi-le
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| Abstract: |
| Effects of three heavy metal ions (Cd2+, Hg2+and Zn2+) on the superoxide dismutase (SOD) activity of the viscera of juvenile sea cucumber (Apostichopus japonicus) were determined through outside body chronic toxicity experimentation. The results showed that the SOD activity changed markedly with prolonged exposure of these ions. Hg2+ (0.009～0.046 mg/L) induced the SOD activity at 24 and 48 hours, reaching the maximum at 96 hours, and then decreased the SOD activity at 144 hours. Effects of Zn2+ (0.195～0.976 mg/L) on the SOD activities were induced at 48 hours, and decreased at 96 and 144 hours. Effects of Hg2+and Zn2+ on the SOD activity were first induced and then inhibited during prolonging the exposure time. Effects of Cd2+ (0.214～1.069 mg/L) on the SOD activities were inhibited at 48 hours, induced at 96 and 144 hours. These results provide a basis for further research on the effects of heavy metal toxicity on antioxidant enzyme system of Apostichopus japonicus. |
| Key words: Apostichopus japonicus Cd2+ Hg2+ Zn2+ SOD |
