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贝类线粒体双单亲遗传研究进展
许然, 胡梦阳, 丁淑荃, 李西雷, 张云龙
安徽农业大学
摘要:
真核生物经历了多次独立演化来保证细胞器的母系遗传模式,然而一些双壳贝类却演化出了一套稳定的可随父、母本传递的独特线粒体遗传模式——双单亲遗传。在双单亲遗传贝类中同时存在两种遗传差异极大的线粒体基因组(F型和M型),可以分别随父本和母本传递给后代。贝类双单亲遗传自首次发现至今已有三十多年,目前其遗传调控机制仍不清楚,本文回顾了独特的双单亲遗传系统及当前研究进展,并展望其可能应用。贝类双单亲遗传的独特性使其成为研究线粒体遗传与进化、核质冲突、性别分化和发育的极佳材料。
关键词:  贝类双单亲遗传  线粒体与核共调控  性别遗传  氧化磷酸化
DOI:
分类号:S917.4
基金项目:国家自然科学基金青年科学基金项目
Research advances in mitochondrial doubly uniparental inheritance in bivalves
xu ran, Hu Mengyang, Ding Shuquan, Li Xilei, Zhang Yunlong
Anhui Agricultural University
Abstract:
Eukaryotes have gone through multiple independent evolution to ensure the maternal inheritance pattern of organelles. However, some bivalves have developed a stable mitochondrial doublely uniparental inheritance system, in which both maternal and paternal mitochondrial DNA (F-type and M-type) can be transmitted to the next generation. It has been more than thirty years since the doublely uniparental inheritance pattern in bivalves was firstly discovered, however, its genetic control is still a mystery. This article reviews the doubly uniparental inheritance system and current research progress, and looks forward to its possible applications. The uniqueness of this system in bivalves can be an excellent material for mitochondrial inheritance and evolution, nucleocytoplasmic conflict, sex determination studies.
Key words:  doubly uniparental inheritance in bivalves  mito-nuclear co-regulation  sexual inheritance  oxidative phosphorylation
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