| 摘要: |
| 在褐藻多酚研究中，传统的观点，即间苯三酚是褐藻多酚的结构单元，在多酚结构规律方面不能清晰地解释6种酚类分子（Fucols, Phlorethol, Fucophloretols， Fuhalols，Eckols，Halogenatedphlorotannins)的成因。作者在理论分析和综合前人实验结果的基础上，提出1，2，3，5-四羟基苯为褐藻多酚的结构单元，它在褐藻细胞中的存在形式为1，2，3，5-四羟基苯-2，5-二硫酸酯或1，2，3，5-四羟基苯-2-硫酸酯，并指出褐藻多酚可能的生成机理，初步为不同种类多酚分子的生成规律提供了一种统一的、清晰的解释。建议今后以1，2，3，5-四羟基苯-2，5-二硫酸酯或1，2，3，5-四羟基本-2-硫酸酯进行褐藻多酚体外合成的实验，以便进一步验证此观点。 |
| 关键词: 结构单元 褐藻多酚 机理 |
| DOI： |
| 分类号: |
| 基金项目:“九五”攻关项目，96-916－04－01号 |
|
| A HYPOTHESIS ON PHAEOPHYCEAE POLYPHENOLS: THEIR STRUCTURAL UNIT AND MECHANISM OF THE FORMATION |
|
Chen Yumin, Yan Xiaojun, Fan Xiao
|
|
Institute of Oceanology , Chinese Academy of Sciences, Qingdao 266071
|
| Abstract: |
| The past study on Phaeophyceae polyphenols is reviewed. The difficulties in the traditional theory are that they cannot clearly explain the formation of different polyphenols (Fucols, Phlorethols, Fucophlorethols, Fuhalols, Eckols, Halogenated phlorotannins) and the existence of vicinal hydroxyl group in fuhalols from the viewpoint that phloroglucinol is the structural unit of the polyphenols. A hypothesis is put forth that 1, 2, 3, 5-tetrahydr0xybenzene is the structural unit existing and taking part in reaction in the form of 1, 2, 3, 5-tetrahydroxybenzene-2, 5-disulfate ester or 1, 2, 3, 5-tetrahydroxy-2-sulfate ester and the biosynthesis of the polyphenols is through the shikimic acid pathway, somewhat like that of phenolics in higher plants. The phenolics and the amino acids of tyr, phe and try in higher plants are biosynthesized through the shikimic acid pathway, and as Phaeophyceae has the above amino acids, then it is mostly likely that the hypothesis holds true. This hypothesis is preliminarily validated by the experiments of Ragan et al., (1979) who surveyed the distributions of 1, 2, 3, 5-tetrahydroxybenzene-2, 5-disulfate ester and 1, 2, 3, 5-tetrahydroxybenzene-2-sulfate ester in 20 species of Phaeophyceae representing 7 orders and 10 families. A common mechanism derived from the hypothesis of the formation of different kinds of polyphenol molecules is illustrated (Fig.3). It is proposed that in the study of Phaeophyceae polyphenols, the synthesis of Phaeophyceae polyphenols from l, 2, 3, 5-tetrahydroxybenzene-2, 5-disulfate ester or 1, 2, 3, 5-tetrahydroxybenzene-2-sulfate ester should be researched for further validation of the hypothesis. |
| Key words: Structural unit, Phaeophyceae polyphenols, Mechanism |
