| 摘要: |
| 根据80-90年代国际上对麻痹性贝毒研究的最新进展，就研究中的几个热点问题进行综合评述，包括：麻痹性贝毒产毒藻的识别；毒素产生机制；毒素监测和分析方法；麻痹性贝毒对海洋生物的影响；麻痹性贝毒对水产养殖业的影响及对策等。概括了麻痹性贝毒研究的现状和研究中亟待解决的问题。中国在麻痹性贝毒毒素研究领域只进行了一些初步的工作，本文结合中国的研究现状，提出以后在此领域内的重点研究方向。 |
| 关键词: 麻痹性贝毒 有害赤潮 产毒机制 分析方法 |
| DOI： |
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| 基金项目:国家自然科学基金资助项目，49576301号 |
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| ADVANCES IN RESEARCH OF PARALYTIC SHELLFISH POISONING |
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YU Ren-cheng,ZHOU Ming-jiang
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Insititule of Oceanology, The Chinese Academy of deiences, Qingdao, 266071
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| Abstract: |
| Recent researches in relation to Paralytic Shellfish Poisoning (PSP) undertaken in the 1980s and 1990s are discussed. The most important advances are listed below. l) Immunological and genetic probes have been used in the identification of toxic algae, which could simplify the process of algae examination and enumeration. These techniques could be further used in field investigations of toxic algal blooms. 2) Bacteria are found to be able to produce PSP. Several strains of toxic bacteria have been isolated and cultured successfully in the laboratory. However, other studies indicated that PSP toxin production is generally related to the toxin algae. Such, the mechanism of toxin production in dinoflagellate remains unclear. 3) New biological and chemical methods have been developed in monitoring and analyzing PSP, such as immunoassays, neuroreceptor binding assays, cytotoxicity bioassays, high performance liquid chromatography (HPLC) and capillary electrophoresis (CE). 4) Studies in an attempt to elucidate toxicological and ecotoxicological effects of PSP have been undertaken. Toxin accumulation and transformation are confirmed in marine organisms of low trophic level, especially in shellfish. 5) Impacts of PSP on mariculture and according management are summarized. Research work on PSP in China started from the beginning of the 1990s. Several research fields with priority are proposed according to the present research status in China. |
| Key words: Paralytic shellfish Poisoning (PSP), Harmful Algal blooms (HAB), Toxin production mechanism, Analytical method |
