| 摘要: |
| 1994年10月，应用国产大网膜402无极性树脂作吸附剂，提取环太湖5个主要入出湖河道中非挥发性有机物进行Ames试验和人体外周血淋巴细胞微核试验，以分析其致突变性。结果表明，4个入湖河道水中有机提取物均显示程度不同的致突变性，而出湖水未显示致突变性。4个样点的有机致突变物组成差异较大。梅梁湖承纳梁溪河和直湖港污水，作为主要饮用水源地，加强其治理刻不容缓。 |
| 关键词: 太湖 有机提取物 致突变 |
| DOI： |
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| 基金项目:国家自然科学基金资助项目，4917017号和水利部“八五”重点研究课题!“太湖水环境生态与富营养化监测研究”部分内容 |
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| MUTAGENICITY OF THE ABSTRACTED NON-VOLATILITY ORGANIC COMPOUNDS FROM FIVE RIVERS AROUND THETAIHU LAKE |
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WU Qing-long,KONG Zhi-ming,CHEN Kai-ning
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1.Nanjing Institute of Geography & Limnology, The Chinese Academy of Sciences, Nanjing, 2100093;2.Department of Environmental Sciences and Engineering, Nanjing University, Nanjing, 210008
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| Abstract: |
| The Ames test and human peripheral lymphocytes micronucleus test are carried out to analyse mutation ability of the abstracted organic substances from five rivers around the Taihu Lake. The results show that organic compounds from 4 of the rivers abstracted have mutagenicity, among which the Liangxi River and Zhihu River (Lvjiangkou) are the most serious and, the Dapu River and Tiaoxi River (the Xiaomeikou) are lessserious. No genetic toxicity was detected from the Taipu River mouth area. In the Lvjiangkou area, the mutagenic pollutants are composed of either frame-shift mutagens or base-pair substitution mutagens; most of the pollutants are indirect mutations. In the Liangxi River mouth area, the mutagenic pollutants are mainly base-pair substitution mutagen which include direct and indirect frame-shift mutagen. In the Xiaomeikou area, the mutagen is only indirect base-pair substitution. In the light of micronucleus test, the mutagens abstracted from the water in Lvjiangkou, Dapu River and Xiaomeikou which can induce the formation of small micronuclei are chromosome breakage, but the pollutants abstracted from the water in the Liangxi River mouth area which can induce the formation of large micronuclei are spindle breakage. The Meiliang Bay of the Taihu Lake where the polluted water of Zhihu River (Lvjiangkou) and Liangxi River charges is the main source of drinking water. Obviously, it is important to control the mutagen pollution to guarantee the health of people around the Taihu Lake. |
| Key words: Taihu Lake, Abstracted organic compounds, Mutagenicity |
