引用本文:	钟静诗,张健,王共明,刘芳,刘奎,王艺欣,刘海超,赵云苹.海参皂苷的制备及结构解析研究进展[J].海洋科学,2022,46(4):133-142.

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海参皂苷的制备及结构解析研究进展
钟静诗^1,2, 张健², 王共明², 刘芳², 刘奎^1,2, 王艺欣^1,2, 刘海超^1,2, 赵云苹²
1.上海海洋大学食品学院, 上海 201306;2.山东省海洋资源与环境研究院, 山东烟台 264006

摘要:

海参皂苷是海参体内的一种次生代谢产物,主要用于抵御捕食者的侵害,具有有效的抗肿瘤、抗帕金森病、免疫调节等作用,应用前景广泛。提取制备海参皂苷是其他研究的基础,而分析结构与活性的关系有助于深入理解其多种生物活性效应产生的原因。本文着重对目前海参皂苷的提取、分离纯化方法及结构分析进行了概述,并对海参皂苷制备方法的优化和结构与生物活性之间的关系进行了分析展望,以期能为相关研究提供参考。

关键词: 海参皂苷提取分离皂苷结构

DOI：10.11759/hykx20200912002

分类号:TS201.2

基金项目:山东省现代农业产业技术体系刺参产业创新团队建设项目(SDAIT-22-07)

Research progress in the preparation and structural analysis of sea cucumber saponins

ZHONG Jing-shi^1,2, ZHANG Jian², WANG Gong-ming², LIU Fang², LIU Kui^1,2, WANG Yi-xin^1,2, LIU Hai-chao^1,2, ZHAO Yun-ping²

1.College of Food Sciences & Technology, Shanghai Ocean University, Shanghai 201306, China;2.Shandong Marine Resource and Environment Research Institute, Yantai 264006, China

Abstract:

Sea cucumber saponins,which are mainly used for defense against predators,are secondary metabolites with anti-tumor,anti-Parkinson's disease,and immune-regulating bioactivities.These also have broad potential applications.The extraction and preparation of sea cucumber saponins are the basis of other studies,and the analysis of the relationship between their structures and activities is helpful for an in-depth understanding of their multiple biological activity effects.In this study,the extraction,separation,purification,and structural analysis of sea cucumber saponins are summarized.Furthermore,the optimization of the preparation of sea cucumber saponins and the relationship between their structures and biological activities are prospected to provide a reference for related research.

Key words: sea cucumber saponins extraction and separation structure of saponins